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As a Physician I base my "nutraceutical" selections in large part by what research studies I can find online in the National Institute of Health database. L-Serine has been shown to contribute to the elaboration of neuronal synapses within the brain (which facilitate transfer of "signals" from one cell to another. In terms of biochemistry L-Serine is base material for manufacture also of various components of brain cell membranes. Studies in humans find improved sleep quality (without induced drowsiness) and especially when combined with DHA some real improvement to memory functions. My use of this supplement is already showing noticeable benefit so I do endorse it's combination with appropriate nootropics for salutary benefit. David S. Parnas, M.D.