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My doc started me on this because of mysterious fatigue and my initial number was low. In less than two months of taking this B12 my level went from 195 to over 1500. So this works, but it works too well if taken every day. I only take this 3 times per week now and will have my level checked again soon. The flavour is great and I haven't had adverse effects as some people have, but every body will react differently. I recommend speaking to your PCP before starting this. *EDIT:* I finally had my level rechecked and it's back in normal range. I'd say 3-4 times a week is enough for most people, but of course consult your doctor first.