508
people found this helpful, as of 2023
ranked #35,411 most helpful
out of 571,544,897 reviews
★★★★☆
If you have SIBO, read this.
We've dealt with SIBO-induced constipation, leading to encopresis, leading to a flare and diagnosis of Crohn's. Miralax made things much worse (if you have SIBO, avoid it at all costs!). Magnesium works really well to soften the stool, but it doesn't do anything to move things out, so to speak. Mineral oil helped get things moving, but not enough. Senna based laxatives worked to some extent, but I was very concerned about long term use and possible cancer risk, and again, they did nothing to address the underlying cause of the problem (SIBO).
We changed to a diet that supposedly works by reducing bad bacteria (SCD and/or combo of low FODMAP). The low FODMAP diet made things worse in the long run (over 2 years, it destroyed the good gut bacteria...you're supposedly only supposed to do it for 4-6 weeks, tops, but researchers didn't discover that until recently). SCD works really well, but again, it doesn't address the reduced motility that (at least in our case) likely caused the SIBO in the first place.
Enter MotilPro. The 5-HTP works as a serotonin precursor (supposedly), which is similar to some of the pharmaceuticals that have been used for IBS over the years. The other stuff (mostly vitamins) helps speed things along. The ginger seems to work on some aspect of the motility receptors in the gut. Overall, this seems to really work! Unfortunately, it seems that, at therapeutic doses, it causes abdominal pain. If we do three pills (the recommended dose) it causes great motility, but pain. If we do two pills, the pain is less but I don't know if it works well enough.
We tried it more than two weeks after finishing antibiotics the first time we dealt with SIBO, so it was likely too late in the game to make a difference. We're currently using it in conjunction with antibiotics this time around, so hoping there is some sort of synergistic effect and that we can drop off the dose as time goes on. Not sure. Our other options seem to be low dose naltrexone or erythromicin, per Dr. Siebecker's research (http://www.siboinfo.com/).
Will update in a few months after things settle down a bit. Right now, I feel it's such a great product, hence the four stars, but in our case, the side-effects my trump the positives. Would give it a five star rating if the side effects were lower.
September 2014 · Health and Household · verified purchase