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I have used Xylitol for at least 6 years now for dry mouth problems. I use many medications and in 2013 almost lost every tooth from acid erosion, a side effect of dry mouth. The only thing I could do was pack course xylitol in my upper gum/lip. The courser grind held together better when packing it densely, but it still needed reapplying during the night. Then I discovered these, they get the job done, but it all comes down to how you use them. It was smart for them to use a plant gum that can be ingested like normal food. They made them round with a rounded top, so they are comfortable with no rough edges. They even thought of (or later discovered) the small dimple needed at the bottom for easier adhesion since there are no flat or straight areas along your gum line. As for overall size and shape, their design is pretty much perfect. So here's the trick to using them. You can try only one, but if you have really dry mouth, you'll need two. Unfortunately, the gum is dry when you first use them. I would tell you to put a drop of water on them and wait, but it takes too long and we all want to go to bed. Instead use what works best, your own spit. It works faster because of the natural digestive enzymes your mouth creates. Hold them one or two at a time and use your tongue to get them very wet on the brown side. Continue holding them or set them down brown side up. Within 30+ seconds you'll need to wet them again - do this at least 3-4 times. I'd tell you to put them in your mouth and just suck on them until they are ready, but you'd waste too much xylitol doing that. The trick is preserving the white stuff. You will learn when it's time to apply them. My test is when they stay wet and how it feels on my tongue. You can feel when they start to get sticky or gummy. This usually takes 3+ minutes. When ready, place one on your upper gum just above a canine tooth - your vampire teeth. Use your tongue to push them as high up as you can and from the outside use your fingers to find a comfortable spot. Once you find a spot where it wants to settle, use your fingers from outside your upper lip (two below it and one on top of it to press) and push lightly to test it out. It will slide around a bit and you'll need to try a few times. Once you can tell you have a good spot, using your fingers from outside your lip, push as hard as is comfortable and position it permanently. If it comes loose, you either didn't have a good spot or it isn't wet enough to adhere. You'll get good at it in 2-3 nights. Also, the thought of it being so sticky that removing it could remove skin is redicilous. Though I will say when it has adhered really well, it can be almost impossible to move with your tongue (which is good), but can be easily removed with your fingers. So forget the idea of not being able to remove it without hurting yourself, this simply can't happen. One more thing to know... I sip warm peppermint tea (sweetened with xylitol) at night. If I'm not careful I could rinse away all of the xylitol which has slowly disolved, you don't want to do this. If you drink water or tea at night, I'd suggest using a straw. The last thing I can think of is keeping your mouth closed. Regardless of these dry mouth mints, if your mouth doesn't stay closed, they won't do much good. If you have a problem with your mouth staying closed at night as I do, speak to your doctor or look for products designed to help. That's it, I hope this helps and good luck.