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I know the recommendation is for 2 caps 3 X/day. This is not advisable unless you have unfettered and unlimited access to toilet facilities. I took one cap yesterday evening and one this morning which caused abdominal spasms soon after. The results, I am not trying to be crude, filled half the toilet. But I feel great! I will repeat this dosing next time I have a day off. I have learned that all Dr. Christopher's remedies are good but take the suggested dosing with a grain of salt and start slow.