Bests & Worsts Reviews from Amazon

Know your rat poison. [...]. [QUOTING BEGIN] The first anticoagulants *Diphacinone* (warfarin, pindone, 1.5 oz.-Diphacinone-0.005% and clorophacinone), are commonly known as the first-generation anticoagulants or multiple-feed rodenticides. These compounds are chronic in their action, requiring multiple feedings over several days to a week or more to produce death. In order to achieve this multiple feeding, the bait must be made available on a continuous basis until the desired control is reached. Where anticoagulants have been used over long periods of time at a particular location, there is an increased potential for a population to become somewhat resistant to the lethal effects of the baits. Resistance of rats to warfarin was first noted in Scotland in 1958, some years following its repeated use. Shortly thereafter, anticoagulant resistance was identified in both rats and house mice in other European countries. Rats and mice that are resistant to warfarin also show some resistance to all first generation anticoagulants, rendering control with these compounds less effective. Although relatively uncommon, a few instances of resistance have been reported in the United States. Warfarin resistance led to the development of the second-generation anticoagulants, bromadiolone and brodifacoum. These compounds are much more potent than the first-generation anticoagulants, making them effective for the control of warfarin-resistant rats and mice. As one feeding can produce death if a sufficient amount of bait is consumed, they are often referred to as single-feed anticoagulants. In commensal situations where rodents are often marginal or reluctant feeders, these compounds can be extremely effective. The effects of these compounds are also cumulative and will result in death after several feedings of even small amounts. As in the case of all anticoagulants, death is delayed for several days following the ingestion of a lethal dose. Where anticoagulant resistance is known or suspected, the use of first-generation anticoagulants should be avoided in favor of the second-generation anticoagulants or one of the non-anticoagulant rodenticides like bromethalin or cholecalciferol." [END QUOTE]