Bests & Worsts Reviews from Amazon

B-6 is a catalyst for amino acids.....so if you take any amino acid alone you need to pair it off with B-6 for the body to utilize it well. I've used other brands (I worked in a health supplement store - major chain, which I won't mention) and comparably the price is very economical and it does produce results. How can you tell? SO....Does it alleviate any symptoms that you have in at least 14 days? It does take at least two weeks to see a difference when it comes to supplements as opposed to pharmaceutical medication. You should always do the research with several reputable websites as to what other synergistic substances work with the amino acid. For example, Taurine and B-6 are sufficient. Diarrhea means the dose you are taking is a bit much. Lysine and/or Proline and B-6 works better with Vitamin C (Ascorbic Acid). Look for reputable sites, like Linus Pauling Institute, that do extensive research with mega foods, that can steer you in the right direction. I don't care about the FDA....they're in the pocket of Pharma. I've been researching and trying supplements for years (thus being hired for a major supplement chain sales). AND....you should check out brands on the GMP (Good manufacturing practices certification) website.