331
people found this helpful, as of 2023
ranked #72,626 most helpful
out of 571,544,897 reviews
★★☆☆☆
Great product to lower blood pressure, support metabolism, liver function, brain/nervous system function, but has Pyridoxine
This product supports metabolism, liver function, brain and nervous system function, and even lower blood pressure which is why I am using it and it worked well for me for that. However there is some new research (The vitamin B6 paradox on researchgate) indicating that taking the pyridoxine form of B6 was found to significantly increase cell death the more you take in SHSY5Y cells, but even in low doses as well. It is the toxic form. It mentions that Lareb reported cases in which even lower doses (2 mg/day) of vitamin B6 in pyridoxine form gave the same complaints of neuropathy as high doses. It also mentions that the pyridoxine form INHIBITS the active B6 form P5P so it is actually working against you when you supplement pyridoxine (not P5P) and working instead toward making you more deficient instead in B6 as you take more pyridoxine. So it appears to not be a good form to take at all even in smaller amounts.
They suggest to replace pyridoxine form of B6 with p5p (pyridoxal phosphate the active form) or pyridoxal. While this particular product is definately low enough that it wont by itself cause great problems if this is all you use that has it, and not needed to stop using due to its low amount, it is just new information that few know about and if there is any way possible to switch the ingredient that would be my suggestion to do so.
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June 2018 · Health and Household · verified purchase