Bests & Worsts Reviews from Amazon

according to people

105
people found this helpful, as of 2023
ranked #249,780 most helpful out of 571,544,897 reviews
★☆☆☆☆
5-HTP should NOT be taken with vitamin B6
I bought this supplement thinking it was only 5-HTP. Turns out I should have read the label before I ordered it. These tablets contain 5-HTP (50mg), Vitamin C(120mg) and Vitamin B6 (10mg). 5-HTP should not be taken simultaneously with vit. B6. Why? 5-HTP is turned into Serotonin using vitamin B6. If you take them both simultaneously, 5-HTP will be turned into Serotonin in your bloodstream and stomach, before it reaches your brain. Then, Serotonin can't pass through the blood-brain barrier so it will just stay in your bloodstream. 5-HTP should pass the blood-brain barrier and then be turned into Serotonin inside the brain where it can improve mood, help sleep, etc. That stuff happens in your brain, not your gut. Furthermore, and this is important, elevated levels of Serotonin in your bloodstream (outside the brain) have been linked to heart damage and such. There haven't been enough studies to prove anything conclusively, but I'd rather stay away and find myself a 5-HTP without vit. B6.
January 2011 · Health and Household · verified purchase
worser bester