Bests & Worsts Reviews from Amazon

I haven't been able to take this supplement long enough to say whether it works or not. The purpose of this review is to warn people that there may be side effects when following the manufacturer's recommended dosages. After less than one week of taking one capsule in the morning and one in the evening with meals, I woke up in the middle of the night with a severe headache, nausea, GI unrest and puffy eyes. It took 5 - 6 hours for these symptoms to resolve. Additionally, the arthritic joints in my hands started to ache and this persisted throughout the day. After going through this again the following night with more severe symptoms, I did an internet search for side effects of DIM and found information about this in a Dr. Oz blog. I then read through some research studies and found that a small number of people experience the same side effects that I did when the dosage is too high. Also, DIM does not clear the average person's blood stream for 18 hours, so there is a cumulative effect when taking DIM twice a day. If you are sensitive to pharmaceuticals as I am, the solution is to experiment with dosages and timing until you find the combination that does not cause side effects. Neither Nature's Way nor BioResponse, L.L.C., the company that manufactures the active ingredient, provides comprehensive warning information on their websites.