Bests & Worsts Reviews from Amazon

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239
people found this helpful, as of 2023
ranked #122,234 most helpful out of 571,544,897 reviews
★★★★★
Very effective product for low folate and related conditions
I recently bought this because I work for a lab company, which tests for mutations in the MTHFR gene, which activates folate to methylfolate. I have the mutation of this gene that causes me to not fully activate folate, even if I get enough from my diet. I started take l-methylfolate from Life Extension about a month ago and I can already tell an improvement in my mood and psychological well-being. My dad's family has a strong genetic hx of psycological disorders ranging from schizophrenia to severe depression. I have been lucky enough not to have gotten any of these, but I have parents and siblings that do, so I'm always concerned about preventing such a disorder from developing. I can say that this product works for me to stay level, happy and reduce even the season affective disorder-like symptoms that I would often get in the winter time. I take 5-6000 mcg/day (I know the bottle says only take 1-2) but we give patients Deplin, which is 15g, so I don't think I'm at risk for overdose because of my genetic variance. I would recommend taking this with an active B12 (methylcobalamin) supplement to prevent B12 deficiency.
March 2013 · Health and Household · verified purchase
the product in question
Life Extension Optimized Folate (L-Methylfolate) 1700 mcg DFE, 180 Veg Tablets (Pack of 2)
4.7★ · 2,933 ratings, as of 2023
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