Bests & Worsts Reviews from Amazon

The drug in Advantage II for Dogs and Advantage II for Cats is exactly the same drugs (Imidacloprid and Pyriproxyfen) at the exact same concentrations. If you buy this "Large Dog" package, you get four 4ml tubes. If you then empty those into a vial or vials, you can use a syringe (without needle) to apply the right dosage to your dogs AND cats. In fact, if your cats are under 10 pounds, you can get 10 cat doses out of each of these vials. That's a real bargain! I am a former Vet Tech and can assure you I have been doing this for years (with Advantage first, and now Advantage II) with ZERO problems. Use the following chart and you will be fine. Cats up to 9 pounds - 0.4ml Cats 10+ pounds - 0.8ml Dogs 3-10 pounds - 0.4ml Dogs 11-20 pounds - 1.0ml Dogs 21-55 pounds - 2.5ml Dogs 55+ pounds - 4.0ml